MEDIA
March 2019
Biofilm forming antibiotic resistant Gram-positive pathogens isolated from surfaces on the International Space Station
“The International Space Station (ISS) is a closed habitat in a uniquely extreme and hostile environment. Due to these special conditions, the human microflora can undergo unusual changes and may represent health risks for the crew. To address this problem, we investigated the antimicrobial activity of AGXX®, a novel surface coating consisting of micro-galvanic elements [...]
Read more Biofilm forming antibiotic resistant Gram-positive pathogens isolated from surfaces on the International Space Station
December 2018
The AGXX® Antimicrobial Coating Causes a Thiol-Specific Oxidative Stress Response and Protein S-bacillithiolation in Staphylococcus aureus
“Multidrug-resistant pathogens, such as methicillin-resistant Staphylococcus aureus (MRSA) pose an increasing health burden and demand alternative antimicrobials to treat bacterial infections. The surface coating AGXX® is a novel broad-spectrum antimicrobial composed of two transition metals, silver and ruthenium that can be electroplated on various surfaces, such as medical devices and implants. AGXX® has been shown [...]
Read more The AGXX® Antimicrobial Coating Causes a Thiol-Specific Oxidative Stress Response and Protein S-bacillithiolation in Staphylococcus aureus
February 2018
A Novel Antimicrobial Coating Represses Biofilm and Virulence-Related Genes in Methicillin-Resistant Staphylococcus aureus
“Methicillin-resistant Staphylococcus aureus (MRSA) has become an important cause of hospital-acquired infections worldwide. It is one of the most threatening pathogens due to its multi-drug resistance and strong biofilm-forming capacity. Thus, there is an urgent need for novel alternative strategies to combat bacterial infections. Recently, we demonstrated that a novel antimicrobial surface coating, AGXX® , [...]
Read more A Novel Antimicrobial Coating Represses Biofilm and Virulence-Related Genes in Methicillin-Resistant Staphylococcus aureus
May 2017
AGXX®: Contribution of Surface Technology to Preventing Biofilms (Part 2)
“Microorganisms are omnipresent and they have important functions in the self cleaning of waters, soils and sediments. Without microbes there would be no life on our planet. But it is only in the last couple of years that scientists have recognized how extraordinarily large their number and significance really is, and how closely related and [...]
Read more AGXX®: Contribution of Surface Technology to Preventing Biofilms (Part 2)
May 2017
AGXX®: Contribution of Surface Technology to Preventing Biofilms (Part 1)
“Microorganisms are omnipresent and they have important functions in the self cleaning of waters, soils and sediments. Without microbes there would be no life on our planet. But it is only in the last couple of years that scientists have recognized how extraordinarily large their number and significance really is, and how closely related and [...]
Read more AGXX®: Contribution of Surface Technology to Preventing Biofilms (Part 1)
October 2016
Antimicrobial surface coating kills multi-resistant pathogens
“Raumfahrzeuge und die Internationale Raumstation (ISS) sind geschlossene Habitate, in welchen die Mikroorganismen, die primär von der Mannschaft stammen, speziellen Umweltbedingungen ausgesetzt sind, die unter anderem durch fehlende Konkurrenz durch Umweltbakterien charakterisiert sind. Dadurch können harmlose kommensale Mikroorganismen überhandnehmen, Oberflächen besiedeln, sogenannte Biofilme aus- bilden und somit eine große Gefahr für die Mannschaft darstellen. Deshalb [...]
Read more Antimicrobial surface coating kills multi-resistant pathogens
May 2015
New antimicrobial contact catalyst killing antibiotic resistant clinical and waterborne pathogens
“Microbial growth on medical and technical devices is a big health issue, particularly when microorganisms aggregate to form biofilms. Moreover, the occurrence of antibiotic-resistant bacteria in the clinical environment is dramatically growing, making treatment of bacterial infections very challenging. In search of an alternative, we studied a novel antimicrobial surface coating based on micro galvanic [...]
Read more New antimicrobial contact catalyst killing antibiotic resistant clinical and waterborne pathogens
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